Anti-Fatigue Effects of Acute Red Ginseng Intake in Recovery from Repetitive Anaerobic Exercise

Ginseng root is one of the traditional medical remedies used for promotion of health and treatment of disease in many Asian countries (1). One particular kind of ginseng, red ginseng, has been the focus of a number of studies and has also demonstrated a positive effect on sports performance as an anti-fatigue (2) and anti-inflammation agent (3) along with ability to mitigate exercise-related muscle damage (4). Most of these studies have focused on medium to long-term intake of red ginseng root. Our study fo-cused on the effect of acute red ginseng intake as a possible nutritional ergogenic aid. We confirmed the effect of acute intake of this plant root on markers of repeated anaerobic capacity namely fatigue, and muscle damage. Subjects of the present study were 11 volunteers, male aged 20.62 ± 0.09 yr. The study was of a " crossover " design. After a one-week washout period, study participants were divided into a placebo group (PG; n=11) and a red ginseng group (RG; n=11, 5 g/day). Repeated anaerobic exercise capacity was evaluated by peak power and mean power measures by five times of the Win-gate Test (Lode Excalibur Ergometer, Lode Medical Technology, Netherlands).. Blood samples were taken at rest, immediately after exercise, at 30 min and 60 min post-exercise. Blood fatigue markers tested were lactate (Accu-trend, Roche, Germany) and ammonia levels (Modular Analytics PE, Roche, Germany); muscle damage markers measured were creatine ki-nase (CK) and lactate dehydrogenase (LDH) levels (Modular Analytics PE, Roche, Germany). In the present study, we used the non-parametric test, Mann-Whitney U-test; this was as the subjects in each group were less than 30, and the data would not allow for a normal distribution (5). Statistical significance was set at P<0.05 (SPSS, Chicago IL, USA). The peak power and mean power were no significant differences in the two groups (Table 1). The results of blood fatigue and muscle damage markers of the RG and PG are presented in Table 2. There was significant difference in the lactate levels between the two groups at 30 min (P= .030) and 60 min (P < .001) and in ammonia levels at 30 min (P = 0.039) recovery from exercise. However , there were no significant differences in CK and LDH between the two groups at any point in time. These results indicate that acute red ginseng intake had only a marginal impact on muscle damage markers, but was effective …